Kisspeptin-10 5mg

Name: Kisspeptin-10 5mg
SKU: PL-5MG-PB02
Price: 65.00 USD
Availability: InStock

Brands PeptideLion

$65.00

in stock

Sku:

PL-5MG-PB02

Brands: PeptideLion

Description

Overview

What is Kisspeptin-10?

Kisspeptin-10 was originally named Metastin after its ability to prevent the spread of cancer (metastasis). Kisspeptin-10 is a peptide produced in the hypothalamus that stimulates the release of gonadotropin-releasing hormone (GnRH) which then causes luteinizing hormone (LH) and follicle-stimulating hormone (FSH) to be released from the pituitary gland. It is used by men who are undergoing testosterone replacement therapy and is often used instead of hCG to boost the body’s testosterone and prevent testicular atrophy.

Potential Benefits of Kisspeptin

Increases testosterone levels
Lowers the risk of heart disease
Boosts immunity
Helps lose weight
Prevents wrinkles and other signs of skin aging
Prevents cancer
Boosts brain power
Treats fertility disorders

Scientific Information

Kisspeptin, collectively describing the neuropeptides cleaved from its 145-amino acid polypeptide precursor (encoded by the KISS1/Kiss1 gene), is a pivotal regulator of reproductive function. Several isoforms exist with a common RF-amide C terminus, including kisspeptin (KP)-54, KP-14, KP-13, and KP-10 (suffix denoting the number of amino acids) although there is some debate as to what extent each isoform is naturally present. Kisspeptin is the endogenous ligand for the kisspeptin receptor (KISS1R/Kiss1r). All of the isoforms have the ability to activate the kisspeptin receptor due to a common C-terminal decapeptide sequence, although KP-54 appears to be the most abundant peptide product in human circulation.

Kisspeptin was originally identified as a metastasis suppressor gene (formerly known as metastin) in human melanoma cell lines. However, landmark studies revealed that KISS1/KISS1R-inactivating mutations in humans or Kiss1r-targeted deletions in transgenic mice, result in a phenotype of delayed puberty and idiopathic hypogonadotropic hypogonadism. Conversely, activating mutations in KISS1R cause central precocious puberty. These pivotal observations established the essential role that kisspeptin plays in the timing of puberty and regulation of the HPG axis.

Research Highlights

Kisspeptin is a peptide, a short chain of amino acids, produced by the hypothalamus in the brain. It plays an important role in human reproduction, aldosterone secretion (which regulates water and salt balance), tumor suppression, and kidney function. As a naturally occurring protein in the body, kisspeptin is crucial for hormone signaling, particularly during puberty and reproduction. Furthermore, researchers created Kisspeptin-10 to replicate the natural effects of Kisspeptin, thereby enhancing its impact on the body.

Reproductive health is closely linked to emotional and mental health in adults, so it’s no surprise that Kisspeptin-10 may influence behavior and mood. Animal studies showed that the peptide enhanced brain activity, boosting motivation and mood in the participants. While more research is needed, experts believe that Kisspeptin-10 may also help reduce anxiety in adults.

Kisspeptin-10 is showing promising results in stopping the spread of cancer. It’s been shown that in suppressing tumor spread and growth, some cancers stop spreading. In one study, the spread of malignant skin cancer was reduced by 95%. Researchers came to this conclusion after it was discovered that peptides can reduce cell cancer migration.