GHK-Cu 50mg

Name: GHK-Cu 50mg
SKU: PL-50MG-PE01
Price: 70.00 USD
Availability: InStock

Brands PeptideLion

$70.00

out of stock

Sku:

PL-50MG-PE01

Brands: PeptideLion

Description

Overview

Copper peptides (GHK-Cu), also known as Cu peptides, are natural tripeptides found in human plasma, saliva, and urine. Over the past four decades, researchers have extensively studied these peptides. As a result, they have shown the ability to facilitate wound healing and skin regeneration. Specifically, they attract capillary cells, promote the formation of new blood vessels, and aid in hair growth. Additionally, these peptides help eliminate damaged cellular debris and initiate the synthesis of crucial proteins needed for tissue healing.

The human copper-binding peptide GHK-Cu (glycyl-l-histidyl-l-lysine) is a small, naturally occurring tripeptide present in human plasma that also can be released from tissues in case of an injury. Since its discovery in 1973, GHK-Cu established itself as a powerful protective and regenerative ingredient, which is currently widely used in skin and hair products.

Benefits of GHK-Cu

Here are some key benefits of copper peptide GHK-Cu:

Tighten loose skin and reverse thinning of aged skin
Repair protective skin barrier proteins
Improve skin firmness, elasticity, and clarity
Reduce fine lines, and depth of wrinkles, and improve the structure of aged skin
Smooth rough skin
Reduce photodamage, mottled hyperpigmentation, skin spots, and lesions
Improve overall skin appearance
Stimulate wound healing
Protect skin cells from UV radiation
Reduce inflammation and free radical damage
Increase hair growth and thickness, enlarge hair follicle size

Scientific Information

The copper-binding tripeptide GHK (glycyl-l-histidyl-l-lysine) naturally occurs in plasma but significantly declines with aging. In addition, research shows that GHK(2+) improves wound healing and tissue regeneration, while also stimulating collagen and decorin production. Furthermore, GHK-Cu supports angiogenesis and nerve outgrowth, enhancing the condition of aging skin and hair. Moreover, it exhibits antioxidant and anti-inflammatory effects. Additionally, GHK-Cu increases cellular stemness and promotes the secretion of trophic factors by mesenchymal stem cells.

GHK’s antioxidant actions have been demonstrated in vitro and animal studies. They include blocking the formation of reactive oxygen and carbonyl species, detoxifying toxic products of lipid peroxidation such as acrolein, protecting keratinocytes from lethal Ultraviolet B (UVB) radiation, and blocking hepatic damage by dichloromethane radicals. In recent studies, GHK has been found to switch gene expression from a diseased state to a healthier state for certain cancers and chronic obstructive pulmonary disease (COPD). The Broad Institute’s Connectivity Map indicated that GHK induces a 50% or greater change of expression in 31.2% of human genes. This paper reviews biological data demonstrating the positive effects of GHK on the skin and proposes interaction with antioxidant-related genes as a possible explanation for its antioxidant activity.

Research Highlights

The GHK peptide is currently a popular ingredient in skin care products. However, the exact mechanism of its actions remains to be established. Currently, all we can say is that both the copper-transporting functions of GHK-Cu and its ability to modify gene expression have biological significance. GHK-Cu can promote activation of wound recovery, appeal of immune cells, antioxidant, and anti-inflammatory consequences, stimulation of collagen and glycosaminoglycan synthesis in pores and skin fibroblasts, and promotion of blood vessel growth.

GHK is a safe, extensively studied compound that has a wealth of positive and health-promoting effects in many tissues and systems. It has been widely used in anti-aging and cosmetic products in humans for decades without any adverse effects and can be easily incorporated in creams, liposomes, foams, or subcutaneous injections.