Description

Overview

What is Epitalon?

Epithalon (also known as Epitalon or Epithalone) is the synthetic version of the polypeptide Epithalamin, which is naturally produced in the pineal gland.

In the world of peptides, Epitalon, also known as Epithalon, is an intriguing player. This small protein-like molecule is made up of a sequence of amino acids. Epitalon has a specific sequence of just four amino acids. It’s a synthetic version of a natural peptide found in the human body, specifically, the pineal gland.

The birth of Epitalon happened in a lab in the late 20th century. A Russian scientist named Vladimir Khavinson was the creator, and his research led him to synthesize this peptide. Khavinson’s studies focused on the natural process of aging as he sought ways to slow it down, aiming to extend the human lifespan. Epitalon peptide stood out due to its association with the pineal gland. This tiny gland in the brain has a big job. It regulates the production of several hormones, including melatonin.

Melatonin is crucial for our sleep and wake cycles. As such, Epitalon has also been the subject of various studies on sleep health and rhythm.

Benefits of Epitalon

As a result of Epitalon’s effect on telomerase production, the benefits are unique and far-reaching and include:

• Increases lifespan by lengthening telomeres in human cells
• Promotes deeper sleep
• Delays and prevents age-related diseases such as cancer, heart disease, and dementia
• Acts as an antioxidant by reducing lipid oxidation and ROS (Reactive oxygen species) along with normalizing T cell function
• Improves skin health and appearance
• Heals injured and deteriorating muscle cells
• Restores and normalizes melatonin levels in those who have lost some pineal function due to aging
• Can increase resistance to emotional stress
• Can epigenetically regulate neuronal differentiation gene expression and protein synthesis in human stem cells

Scientific Information

It was shown that AEDG peptide (Ala-Glu-Asp-Gly, Epitalon) regulates the function of the pineal gland, the retina, and the brain. AEDG peptide increases longevity in animals and decreases experimental cancerogenesis. AEDG peptide induces neuronal cell differentiation in retinal and human periodontal ligament stem cells. The aim of the study was to investigate the influence of AEDG peptide on neurogenic differentiation gene expression and protein synthesis in human gingival mesenchymal stem cells, and to suggest the basis for the epigenetic mechanism of this process. AEDG peptide increased the synthesis of neurogenic differentiation markers: Nestin, GAP43, β Tubulin III, Doublecortin in hGMSCs. AEDG peptide increased Nestin, GAP43, β Tubulin III and Doublecortin mRNA expression by 1.6–1.8 times in hGMSCs. Molecular modelling method showed that AEDG peptide preferably binds with H1/6 and H1/3 histones in His-Pro-Ser-Tyr-Met-Ala-His-Pro-Ala-Arg-Lys and Tyr-Arg-Lys-Thr-Gln sites, which interact with DNA. These results correspond to previous experimental data. AEDG peptide and histones H1/3, H1/6 binding may be one of the mechanisms which provides an increase of Nestin, GAP43, β Tubulin III, and Doublecortin neuronal differentiation gene transcription. AEDG peptide can epigenetically regulate neuronal differentiation gene expression and protein synthesis in human stem cells.

Research Highlights

Epitalon is considered the “fountain of youth” peptide and has been studied for over 35 years. Epitalon works in the pineal gland of the brain and its primary role is to increase the natural production of a specific enzyme. This enzyme works to reproduce protective parts of our DNA. Additionally, Epitalon promotes a natural and healthy sleep cycle while making sure cortisol and other stress hormones are not elevated throughout the day. This is critical as these hormones remaining high can lead to excess abdominal weight gain.

Epitalon offers a number of benefits that can help combat the symptoms of aging. It also helps with mood and acts as an antioxidant. Numerous studies have shown the importance of telomerase production and telomere rejuvenation in fighting the symptoms of aging. As Epitalon has been shown to increase the production of telomerase, which in turn strengthens and lengthens telomeres, this means that Epitalon can play a vital role in decreasing the aging process and thus extend human longevity.

No adverse reactions were noted for Epitalon in the more than 100 scientific studies that have already happened to this peptide.

References

1. Epitalon: The Longevity Peptide – Body Rejuvenation MD: https://www.bodyrejuvenationmd.com/lifespan-longevity-anti-aging/epitalon-the-longevity-peptide/
2. Epithalon – Transform You: https://www.transformyou.com/epithalon
3. Epitalon – NCBI: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037223/
4. Epithalon – Focal Point Vitality: https://focalpointvitality.com/epitalon-peptide/

Additional information

size	20mg, 50mg